OTRIVINE 0,5 MG/ML FL 10 ML

• non-allergic rhinitis (head colds)
• seasonal and non-seasonal allergic rhinitis
• sinusitis (helps eliminate secretions)
• otitis media (as an adjuvant to nasopharyngeal decongestion)

Children aged 2 to 6 years

• 1 to 2 drops in each nostril, 1 to 3 times a day
• Minimum interval between 2 applications: 8 to 10 hours

Otrivine,0.5 mg/ml, solution:Xylometazoline hydrochloride 0.5 mg per ml (corresponding to 0.44 mg/ml xylometazoline).
(12.5 µg xylometazoline hydrochloride per drop, 40 drops per ml).

Notable excipients: This medicine contains benzalkonium chloride as a preservative. This substance may be irritant and cause skin reactions.

Short-term symptomatic treatment (maximum 3 to 5 days) of nasal congestion in certain conditions such as:- non-allergic rhinitis (common cold)
- seasonal and non-seasonal allergic rhinitis
- sinusitis (facilitates the elimination of secretions)
- otitis media (as an aid in decongesting the nasopharynx)

The excipients sorbitol and methylhydroxypropylcellulose present in Otrivine may help prevent the nasal mucosa from drying out.

As with all nasal preparations containing a vasoconstrictor, Otrivine cannot be used as a maintenance treatment.

Otrivine 0.5 mg/ml is intended for children aged 2 to 12 years inclusive.

Otrivine 0.5 mg/ml solution for nasal instillation for children aged 2 to 12 years:

Children aged 2 to 6 years: under parental supervision.
1 to 2 drops, 1 to 3 times a day. Allow an interval of 8 to 10 hours between 2 administrations. No more than 3 administrations per nostril per day.

Children aged 6 to 12: under parental supervision.
2 to 4 drops in each nostril, 2 to 3 times a day. Allow an interval of 8 to 10 hours between 2 doses. No more than 3 administrations per nostril per day.

Use of the solution for nasal instillation :
1. Blow your nose.
2. Tilt your head back as far as is comfortable or, if you are lying in bed, let your head hang over the edge of the bed.
3. Administer the drops into each nostril and keep your head tilted back for a short time, so that the drops can distribute themselves in the nasal cavity.
4. Clean the dropper and leave it to dry before returning it to the bottle.

To prevent the infection spreading, the bottle may only be used by 1 person.

• Hypersensitivity to the active substance or to any of the excipients mentioned in section 6.1 or to other sympathicomimetic amines - Angle-closure glaucoma.
• Patients treated with MAOIs, due to the risk of severe hypertensive crisis.
• Atrophic rhinitis.
• Otrivine cannot be used after trans-sphenoidal hypophysectomy or after nasal or buccal surgery where the dura has been exposed.

Otrivine 0.5 mg/ml should not be administered to children under 2 years of age.

Otrivine is a nasal decongestant based on xylometazoline (0.5mg/ml).
In the event of a blocked nose due to a cold or sinusitis, Otrivine 0.5mg/ml:
- Clears the nose in a few minutes.
- Relieves for up to 10 hours.
- Helps prevent irritation of the nasal mucosa.
- For children aged 2 to 12.
- Xylometazoline has no effect on the function of the ciliary epithelium.

The presence of sorbitol and methylhydroxypropylcellulose as excipients in Otrivine may help prevent the nasal mucosa from drying out.